Table 1. Demographic and clinical data in clinical study cohort-1 and cohort-2.
Healthy controls (n = 38) | Study cohort-1 (n = 38) | Study cohort-2 (n = 13) | |
---|---|---|---|
Gender (male : female) | 30: 8 | 30: 8 | 9: 4 |
Age (yr)† | 52.6 (40–69) | 53.5 (40–64) | 53.0 (43–63) |
HBV positive | — | 31 (81.6%) | 10 (76.9%) |
Primary disease (HCC: others) | — | 26: 12 | 12: 1 |
Median ALT before LTx (U/L)* | 22.5 ± 1.2 | 44.5 ± 380.9 | 66.9 ± 50.1 |
Median AST before LTx (U/L)* | 19.2 ± 1.7 | 66.5 ± 257.9 | 50.2 ± 43.9 |
Median AFP before LTx (ng/mL)† | — | 10.0 (1–6040) | 116.2 (2.8–8232) |
Abbreviations: HBV, hepatitis B virus; HCC, hepatocellular carcinoma; AFP, alpha-fetoprotein; LTx, liver transplantation.
†Data are expressed as medians (range).
*Data are expressed as mean ± S.D. −, not available.