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. 2016 Jan 22;6:19492. doi: 10.1038/srep19492

Figure 5. TASK-1 cap structure model based on domain-swapped TREK-2.

Figure 5

TASK-1 cap structure illustrated after 100 ns of MD simulations. The two different subunits are shown in gray and light gray. TASK-1 cap model with the residues identified essential for channel expression, which are involved in intersubunit interactions. Pairs of residues that interact with each other are illustrated using the same color code. (a) Complete structure of the TASK-1 model. (b) Zoom-in to the boxed area of (a) illustrating interacting residues and their distances, and (c) after 45° rotation or (d) after additional tilting of 45° out of the plane. (e) Close-up in the cap on specific pairs of amino acids involved in intersubunit interactions.