Table 1. Intersubunit interactions in a TASK-1 homology model based on domain-swapped TREK-2.

The diagonal line, highlighted in gray, indicates the distance to the same residue in the neighboring subunit of the dimeric protein. Intersubunit distances are listed under the diagonal line and are written black. Intrasubunit interactions which should be less relevant for the dimerization of the channel are listed over the diagonal line and written in a light gray. Distances are measured from a predefined carbon of the amino acid side chain, lacking also the hydrogen atoms, and thus a more remote cut-off of 6 Å was used (Supplementary Fig. S3 and Methods). Intersubunit distances under 6 Å are indicated in red. Mean ± SDEV.