Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Jan 21;6:19620. doi: 10.1038/srep19620

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2016, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

(a) PCR model-predicted gene expression levels. The x-axis indicates centred average gene expression level associated with each of the 258 cis-regulatory elements. The y-axis indicates gene expression level by PCR model. Blue and red points indicate myoblasts and myotubes, respectively (n = 512). (b) The wave shape and its PC weights of the best NP pattern for gene expression prediction by PCR are shown. The x-axis indicates relative position from the cis-regulatory element (the centre is at x = 0), the y-axis indicates scaled and centred MNase-Seq signal intensity. The left-bottom bars represent the weights of PC1-5 (labelled as 1–5) of the wave shape. (c) The best NP pattern for predicting gene expression derived by ridge regression analysis. The six boxes show the result of the best NP patterns with various bias parameters and λ values. The λ values are shown in the head of each box. The x and y-axes are the same as in (b). (d) Functional profile of ENCODE TFBS data in mouse C2C12 cells. The weight of each component is presented as a pie chart where the composition ratios (%) of the five components are indicated. Numbers correspond to PC1-5. Composition ratios from components other than PC1–5 are shown as blank regions. (e) Functional profiling of RNAP2-Ser5ph in myoblasts/myotubes shown in (d).