Table 2. The haplotype analysis of rs11642873 and rs17445836 in BD patients and controls.
Haplotype | Case (freq., %) | Control (freq., %) | P value | Pc value | OR (95% CI) |
---|---|---|---|---|---|
IRF8(rs11642873-rs17445836) | |||||
A G | 1942(90.7) | 3512.6(85.5) | 6.41 × 10−9 | 2.60 × 10−8 | 1.646(1.389–1.950) |
C G | 99(4.6) | 239.4(5.8) | 0.046 | NS | 0.783(0.616–0.996) |
C A | 53(2.5) | 224.6(5.5) | 5.00 × 10−8 | 2.00 × 10−7 | 0.439(0.324–0.595) |
A A | 48(2.2) | 131.4(3.2) | 0.031 | NS | 0.694(0.496–0.970) |
Pc: Bonferroni corrected p value, multiplied by 4. NS, not significant.