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. 2016 Jan 20;6:19197. doi: 10.1038/srep19197

Figure 2. Loss of Cx40 results in abnormal electrical activation of the ventricles without morphological defects of the VCS.

Figure 2

(a) Representative surface ECG trace shows QRS prolongation and notched R’ wave in Irx3+/+;Cx40EGFP/EGFP mice. (b) Optical mapping in Irx3+/+;Cx40EGFP/EGFP heart exhibited RBB block, similar to Irx3−/− heart. (c,d) VCS structures visualized by Cx40-EGFP in both LV (c) and RSW (d) are normal in Irx3+/+;Cx40EGFP/EGFP mice. LV, left ventricle; RSW, right ventricular septal wall; HB, his-bundle; RBB, right bundle branch.