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. 2016 Jan 20;6:19197. doi: 10.1038/srep19197

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Copyright © 2016, Macmillan Publishers Limited

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(a) Representative ECG traces of Irx3^+/+ and Irx3^−/− mice at P0 and P4. Analysis of neonatal mouse ECGs revealed that there are no differences in PQ (b) and QTc (d) intervals between Irx3^+/+ and Irx3^−/− mice all different developmental stages (i.e. P0, P4 and 8 week old (8 W)). On the other hand, QRS intervals of Irx3^−/− mice, (c) that were not significantly different at P0 compared to controls, became prolonged from P4 onwards. (e) The prevalence of notched R’ wave, an indicator of right bundle branch block. *P < 0.05 vs. Irx3^+/+ mice.