Table 2.
Percent bias in different populations across clinically relevant eGFR ranges. Means with 95% confidence intervals that include zero are not significantly different from iothalamate corrected mGFR.
| eGFR | Potential Donors | CKD Patients | Kidney Recipients | Other Organ Recipients |
|---|---|---|---|---|
| Overall | ||||
| eGFRCr | −11.6 (−14, −8.9) | −0.8 (−3.0, 1.3) | 0.5 (−2.2, 3.2) | 1.3 (−2.2, 4.9) |
| eGFRCys | 4.8 (1.4, 8.1) | 0.1 (−1.9, 2.2) | −5.4 (−7.8, −3.0) | −7.7 (−10, −5.4) |
| eGFRCr-Cys | −2.7 (−5.4, 0) | −1.9 (−3.6, −0.2) | −4.8 (−7.0, −2.6) | −5.6 (−7.8, −3.5) |
| ≥90 mL/min/1.73m2 | ||||
| eGFRCr | −5.8 (−9.7, −1.9) | 5.0 (1.5, 8.6) | 29 (11.6, 46.4) | 13.5 (5.5, 22) |
| eGFRCys | 8.5 (4.9, 12.1) | 8.2 (4.7, 11.8) | 14.5 (4.8, 24.2) | 7.4 (0.8, 14) |
| eGFRCr-Cys | −1.4 (−4.5, 1.8) | 3.1 (−0.1, 6.3) | 6.7 (−3.4, 16.7) | 5.5 (−0.6, 12) |
| 60–89 mL/min/1.73m2 | ||||
| eGFRCr | −15 (−18.9, −11.2) | −4.0 (−7.4, −0.7) | 7.1 (2.1, 12.2) | 6.4 (−2.0, 15) |
| eGFRCys | −7.9 (−15.2, −0.6) | −2.4 (−5.7, 0.9) | 3.6 (0.3, 7) | −2.6 (−6.8, 1.5) |
| eGFRCr-Cys | −4.3 (−9.7, 1.1) | −5.0 (−7.5, −2.4) | −0.7 (−3.9, 2.6) | −4.7 (−8.6, −0.8) |
| 45–59 mL/min/1.73m2 | ||||
| eGFRCr | −20.5 (−27.3, −13.7) | −3.5 (−9.3, 2.3) | −6.3 (−9.7, −2.9) | −0.5 (−6.5, 5.6) |
| eGFRCys | −17.2 (−29.5, −4.8) | −7.3 (−12.3, −2.4) | −9.7 (−12.7, −6.8) | −7.2 (−12, −2.4) |
| eGFRCr-Cys | −18.5 (−28.7, −8.3) | −4.2 (−8.6, 0.1) | −7.9 (−10.8, −4.9) | −7.5 (−11, −3.7) |
| 30–44 mL/min/1.73m2 | ||||
| eGFRCr | – | −2.5 (−9.0, 4.1) | −2.9 (−7.9, 2.0) | −4.5 (−10, 1.5) |
| eGFRCys | – | −5.5 (−11, 0.0) | −11.3 (−16, −6.8) | −14.2 (−19, −9.7) |
| eGFRCr-Cys | – | −3.7 (−8.7, 1.3) | −7.8 (−12, −3.7) | −6.9 (−11, −2.5) |
| <30 mL/min/1.73m2 | ||||
| eGFRCr | – | 0.3 (−6.2, 6.8) | 5.2 (−10, 21) | −5.1 (−16, 6.0) |
| eGFRCys | – | 4.4 (−1.9, 11) | −6.1 (−17, 5.1) | −15.5 (−21, −10) |
| eGFRCr-Cys | – | 0.7 (−4.6, 6) | −0.1 (−12, 12) | −7.5 (−15, −0.1) |