Table 3. Genes encoding for hypothetical proteins with altered transcription in mock-inoculated microglia clones.
| Feature symbol | FC | Identity | Conserved domains on | E-value |
|---|---|---|---|---|
| LOC101104567¶ | 9.36 | Envelope glycoprotein-like | Env polyprotein* | 2.18E-110 |
| LOC101122294 | 3.67 | Membrane cofactor protein-like | Complement control modules | 6.90E-12 |
| LOC101116132 | -1.46 | 40S ribosomal protein S3a-like | Ribosomal S3Ae family | 1.21E-100 |
| LOC101106384 | -1.53 | Thymosin beta-4-like | Thymosin beta-4 family | 4.19E-14 |
| LOC101110467¶ | -1.66 | Transmembrane protein 45A-like | Family of unknown function (DUF716) | 3.44E-41 |
| LOC101103097 | -1.68 | Translationally-controlled tumor protein-like | Translationally controlled tumor protein | 1.23E-60 |
| LOC101104079 | -1.81 | Cystatin C | Cystatin-like domain | 8.98E-36 |
| LOC101109246 | -1.82 | 40S ribosomal protein S4-like | KOW motif of ribosomal protein S4 | 2.10E-28 |
| LOC101105484¶ | -2.11 | Ferritin heavy chain-like | Eukaryotic ferritins | 1.10E-93 |
| LOC443512¶ | -2.16 | Collagen I pro-alpha 2 chain precursor | Fibrillar collagens C-terminal domain | 1.18E-134 |
| LOC100037666 | -2.20 | Ribosomal protein S11 | 40s ribosomal protein S11 | 5.93E-91 |
| LOC100037669 | -2.23 | Niemann-Pick disease type C2 | Niemann-Pick type C2 | 7.10E-54 |
| LOC101104961 | -2.27 | 40S ribosomal protein S24-like | 40S ribosomal protein S24 | 1.52E-43 |
| LOC101104661 | -2.34 | Growth-regulated alpha protein-like | Chemokin_CXC | 1.21E-24 |
| LOC101103639 | -2.48 | Uncharacterized LOC101103639 | None | None |
| LOC100037665 | -2.52 | Ribosomal protein s6 | Ribosomal protein S6e | 2.60E-101 |
| LOC780524 | -2.54 | Ribosomal protein S2 | Ribosomal protein S5, N-terminal domain | 3.21E-30 |
| LOC100101231¶ | -2.56 | Collagen type III alpha 1 | Fibrillar collagens C-terminal domain | 7.92E-138 |
| LOC101122112 | -2.68 | 60S ribosomal protein L36a-like | 60S ribosomal protein L36a | 1.93E-95 |
| LOC100037664 | -2.76 | Ribosomal protein L35a | Ribosomal protein L35Ae | 3.17E-53 |
| LOC101112245 | -2.77 | Adenosylhomocysteinase-like | S-adenosylhomocysteine hydrolase | 0E+00 |
| LOC100037667 | -3.29 | Ribosomal protein S12 | Ribosomal protein L7A3/L30e/S12e/Gadd45 family | 8.51E-30 |
| LOC101102096 | -3.81 | Laminin receptor 1 pseudogene | 40S ribosomal protein SA* | 9.07E-125 |
| LOC101108131¶ | -3.89 | Complement C3-like | Proteins similar to C3, C4, C5 of vertebrate complement | 1.90E-94 |
| LOC101102861¶ | -5.31 | Phospholipid scramblase 2-like | Scramblase | 1.42E-122 |
FC: fold change in transcription (relative to highly permissive microglia).
*: Protein sequence manually generated prior to identification of conserved domains.
¶: Genes with altered transcription in both treatment-matched comparisons.