Table 4. Genes encoding for hypothetical proteins with altered transcription in scrapie-inoculated microglia clones.
| Gene symbol | FC | Identity | Conserved domains | E-value |
|---|---|---|---|---|
| LOC101104567¶ | 8.31 | Envelope glycoprotein-like | Env polyprotein* | 2.18E-110 |
| LOC101105484¶ | -1.55 | Ferritin heavy chain-like | Eukaryotic ferritins | 1.10E-93 |
| LOC101110467¶ | -1.68 | Transmembrane protein 45A-like | Family of unknown function (DUF716) | 3.44E-41 |
| LOC101103238 | -2.06 | Uncharacterized LOC101103238 | Chemokine_CXC | 2.09E-23 |
| LOC443512¶ | -2.27 | Collagen I pro-alpha 2 chain precursor | Fibrillar collagens C-terminal domain | 1.18E-134 |
| LOC101108131¶ | -3.08 | Complement C3-like | Proteins similar to C3, C4, C5 of vertebrate complement | 1.90E-94 |
| LOC100101231¶ | -3.13 | Collagen type III alpha 1 | Fibrillar collagens C-terminal domain | 7.92E-138 |
| LOC101102861¶ | -6.29 | Phospholipid scramblase 2-like | Scramblase | 1.42E-122 |
FC: Fold change in transcription (relative to highly permissive microglia).
*: Protein sequence manually generated prior to identification of conserved domains.
¶: Genes with altered transcription in both treatment-matched comparisons.