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. Author manuscript; available in PMC: 2017 May 1.
Published in final edited form as: Magn Reson Med. 2015 Jun 16;75(5):1967–1977. doi: 10.1002/mrm.25793

Figure 3.

Figure 3

The optimal scan time depends on the Ktrans value for the Patlak model, as long scan times and high Ktrans will lead to significant backflux and poor results. Scanning longer than 15 minutes is only beneficial for the very lowest Ktrans values, and longer than 5 minutes leads to sharp drops in the K-CNR of Ktrans > 10*10−3/min.