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. 2016 Jan 25;12(1):e1005820. doi: 10.1371/journal.pgen.1005820

Fig 5. Western blots showing the relative expression of exogenously expressed CNOT7 and the D40A mutant in 6DT1 (A), 4T1 (B) and Mvt1 (C).

Fig 5

The ectopically expressed CNOT7 migrates slightly higher than the endogenous band due to the addition of the FLAG epitope tag. The cell lines injected for 4T1 and Mvt1 experiments are indicated below the panels by arrows. Primary tumor burden for the CNOT7 or D40A mutant cell lines are indicated in panels D-F. Surface pulmonary metastases (G-I) and metastases normalized for primary tumor mass (J-L) are displayed on the last two rows of the figure. N.S. = not significantly different. * = p< 0.05; ** = p< 0.01; *** = p< 0.001.