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. 2016 Jan 25;11(1):e0147817. doi: 10.1371/journal.pone.0147817

Table 5. Psychological state and CRHR2 SNPs in IBS patients and controls.

Haplotype IBS vs. controls (P value) haplotype effect (P value) group-haplotype interaction (P value)
PSS
rs4722999—rs2267710
TTTC 0.047 0.035 ns
TTTT* 0.041 0.005 ns
CTTT* 0.041 0.005 ns
CCTT* 0.041 0.005 ns
TCTT* 0.041 0.005 ns
CTTC 0.047 0.035 ns
CTCC ns 0.041 ns
CCCT ns 0.014 ns
STAI (state)
rs4722999—rs2267710
TTTC ns 0.035 ns
TTTT* ns 0.020 ns
CTTT* ns 0.020 ns
CCTT* ns 0.020 ns
TCTT* ns 0.020 ns
CTTC ns 0.035 ns
STAI (trait)
rs4722999—rs2267710
TTTT* ns 0.020 ns
CTTT* ns 0.020 ns
CCTT* ns 0.020 ns
TCTT* ns 0.020 ns
rs2284217—rs2284220
GG ns ns 0.021
SDS
rs4722999—rs2267710
TTTT* ns 0.012 ns
CTTT* ns 0.012 ns
CCTT* ns 0.012 ns
TCTT* ns 0.012 ns

Data without significance were not shown.

*: The four haplotype carriers (T-T-T-T, C-T-T-T, C-C-T-T, and T-C-T-T) were all the same individuals.