Table 5. Psychological state and CRHR2 SNPs in IBS patients and controls.
Haplotype | IBS vs. controls (P value) | haplotype effect (P value) | group-haplotype interaction (P value) | |
---|---|---|---|---|
PSS | ||||
rs4722999—rs2267710 | ||||
TTTC | 0.047 | 0.035 | ns | |
TTTT* | 0.041 | 0.005 | ns | |
CTTT* | 0.041 | 0.005 | ns | |
CCTT* | 0.041 | 0.005 | ns | |
TCTT* | 0.041 | 0.005 | ns | |
CTTC | 0.047 | 0.035 | ns | |
CTCC | ns | 0.041 | ns | |
CCCT | ns | 0.014 | ns | |
STAI (state) | ||||
rs4722999—rs2267710 | ||||
TTTC | ns | 0.035 | ns | |
TTTT* | ns | 0.020 | ns | |
CTTT* | ns | 0.020 | ns | |
CCTT* | ns | 0.020 | ns | |
TCTT* | ns | 0.020 | ns | |
CTTC | ns | 0.035 | ns | |
STAI (trait) | ||||
rs4722999—rs2267710 | ||||
TTTT* | ns | 0.020 | ns | |
CTTT* | ns | 0.020 | ns | |
CCTT* | ns | 0.020 | ns | |
TCTT* | ns | 0.020 | ns | |
rs2284217—rs2284220 | ||||
GG | ns | ns | 0.021 | |
SDS | ||||
rs4722999—rs2267710 | ||||
TTTT* | ns | 0.012 | ns | |
CTTT* | ns | 0.012 | ns | |
CCTT* | ns | 0.012 | ns | |
TCTT* | ns | 0.012 | ns |
Data without significance were not shown.
*: The four haplotype carriers (T-T-T-T, C-T-T-T, C-C-T-T, and T-C-T-T) were all the same individuals.