Table 1. Prevalence of somatic KCNJ5 mutation across different countries.
City (Country) | Number of APA | KCNJ5 mutated, n (%) | G151R (%) | L168R (%) | Other mutations | Reference |
---|---|---|---|---|---|---|
Seoul (Korea) | 66 | 47 (71.2) | 66.0 | 34.0 | - | Our study |
Maebashi (Japan) | 23 | 15 (65.0) | 80.0 | 20.0 | - | 4 |
Yokohama (Japan) | 108 | 75 (69.4) | 60.5 | 39.5 | T158A (n = 1), E145Q (n = 2) | 17 |
Shanghai (China) | 168 | 129 (76.8) | 51.9 | 46.5 | T158A (n = 1), T148-T149insR (n = 1) | 12 |
Beijing (China) | 114 | 86 (75.4) | 50.0 | 45.3 | T158A (n = 2) | 19 |
Taipei (Taiwan) | 148 | 91 (61.5) | 49.5 | 45.1 | T158A (n = 1), I157del (n = 1) | 18 |
Paris (France) | 199 | 74 (37.2) | 62.2 | 37.8 | - | 9 |
München (Germany) | 93 | 32 (34.4) | 56.3 | 43.7 | - | 9 |
Berlin (Germany) | 23 | 11 (47.8) | 45.5 | 54.5 | - | 9 |
Torino (Italy) | 73 | 29 (39.7) | 65.5 | 27.6 | T158A (n = 1), W126R (n = 1) | 9 |
Padova A (Italy) | 37 | 14 (37.8) | 57.1 | 42.9 | - | 9 |
Padova B (Italy) | 66 | 15 (22.7) | 66.7 | 33.3 | - | 10 |
Padova C (Italy) | 37 | 14 (37.8) | 57.1 | 42.9 | - | 10 |
Rome (Italy) | 43 | 6 (14.0) | 33.3 | 66.7 | - | 10 |
Cambridge (United Kingdom) | 46 | 20 (43.5) | 55.0 | 40.0 | I157del (n = 1) | 18 |
APA, aldosterone-producing adenoma.