Table 1. Characteristics of septic and control rats: clinical records from the onset of septic shock to the end of the experiment and effects of different enteral nutrition formulations.
| SHAM (n = 5) | CLP-HN (n = 12) | CLP-AF (n = 15) | CLP-AFA (n = 21) | |
|---|---|---|---|---|
| Body Weight (g) | 428 ± 28 | 389 ± 30 | 390 ± 22 | 379 ± 25 |
| MAP (mmHg) | ||||
| Baseline | 123 ± 14 | 78 ± 9* | 80 ± 9* | 75 ± 9* |
| End of experiment | 103 ± 19 | 88 ± 8 | 91 ± 7 | 97 ± 8 |
| HR (bpm) | ||||
| Baseline | 338 ± 57 | 344 ± 22 | 351 ± 13 | 339 ± 11 |
| End of experiment | 306 ± 54 | 381 ± 25 | 349 ± 19 | 362 ± 19 |
| CBF (mL/min) | ||||
| Baseline | 4.8 ± 1.5 | 4.5 ± 0.7 | 6.2 ± 0.8 | 5.0 ± 0.5 |
| End of experiment | 3.8 ± 1.7 | 3.4 ± 0.5 | 3.2 ± 0.4 | 3.2 ± 0.5 |
| Lactate (mmol/l) | 1.0 ± 0.4 | 5.2 ± 1.1* | 3.3 ± 0.4* | 3.4 ± 0.4* |
Septic (CLP-HN, CLP-AF, CLP-AFA) and SHAM rats were treated with different enteral nutrition formulations during 4 days. Baseline was recorded 18 hours after CLP or SHAM surgery (performed on the 4th day) and rats were monitored during 4 hours (from the 18th to the 22nd hours). MAP: mean arterial pressure, HR: heart rate, bpm: beat per minute, CBF: carotid blood flow, NE: norepinephrine. Data are expressed as mean ± SD, p<0.05: * vs. SHAM.