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. 2016 Jan 25;11(1):e0147717. doi: 10.1371/journal.pone.0147717

Fig 3. Effects of cerulenin on GSC viability and invasion.

Fig 3

(A) Effects of cerulenin on GSC viability. Cell viability was assessed 0, 24, 48 h treatment with 0, 20, 30, 40 μM cerulenin by MTS assay. G144 and Y10 cell viability was significantly reduced by 30, 40 μM cerulenin. * P < 0.05, # P < 0.01, ** P< 0.001 (B) De novo lipogenesis using glucose as carbon source in GSCs and GSCs incubated with 20 μM cerulenin. * P < 0.05 (C) Quantitative results of Matrigel invasion assay. Each column represents mean ± SEM for three independent experiments. * P < 0.05.