Fig 7. In vivo effects of pharmacological inhibition of A3AR.
Diabetic rats were treated with the adenosine A3 receptor antagonist MRS1220 from days 31 to 60 post diabetes induction, A. Representative inmunohistochemical detection of α-SMA in cortical areas of kidney sections from untreated (control), diabetic (vehicle-treated rats) and MRS1220-treated diabetic rats. Original magnifications 400X. B. The graph shows quantitative results derived from staining analyses of consecutive field from three animals per group using the UN-SCANIT 2.0 software. Values of control samples were normalized to 1. * P < 0.05 vs control.