Table 1. Physiological parameters in streptozotocin-induced diabetic rats.
1 month | 4 months | ||||
---|---|---|---|---|---|
control | diabetes | control | diabetes | ||
Body weight (gr) | 518 ± 53 | 315 ± 74 * | 593 ± 115 | 284 ± 120 * | |
Glycaemia (mg/dl) | 124 ± 21 | 449 ± 188 * | 133 ± 99 | 482 ± 80 * | |
Relative kidney weight (g/Kg) | Left | 6.24 ± 0.6 | 10.6 ± 1.8 * | 5.35 ± 0.3 | 10.93 ± 1.5 * |
Right | 5.47 ± 0.7 | 9.7 ± 1.9 * | 5.32 ± 0.8 | 10.60 ± 1.7 * | |
Proteinuria (mg/mg creatinine) | 1.8 ± 0.3 | 2.3 ± 0.6 | 2.5 ± 0.6 | 4.9 ± 0.6 * | |
Urinary Urea (mg/mg creatinine) | 47.6 ± 5.9 | 50.4 ± 8.5 | 39.1 ± 3.5 | 87.0 ± 10.2 * | |
Urinary Uric Acid (mg/mg creatinine) | 0.079 ± 0.083 | 0.140 ± 0.09 | 0.077 ± 0.03 | 0.172 ± 0.05 * |
*, P < 0.05 diabetes vs control (n = 6).