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. 2016 Jan 25;11(1):e0147391. doi: 10.1371/journal.pone.0147391

Fig 5. Measurement of β-cell apoptosis after empagliflozin treatment.

Fig 5

TUNEL assay of whole pancreata was performed from T1DM mice after treatment with empagliflozin (3mg/kg) or vehicle for 8 days. (A) Double fluorescence labeling using insulin and terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL) assay in pancreas sections from vehicle- and empagliflozin-treated mice. (B) Bar graphs show the % of TUNEL positive β-cell/total number of β-cells. Data are expressed as mean±S.E.M. Scale bar = 100 μm.*P<0.05 vs vehicle group. (n = 10–12 for each group).