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(A) The Fusarium verticillioides pathway for metabolic detoxification of BOA into N-(2-hydroxyphenyl)malonamic acid. The FDB1 locus facilitates hydrolysis of BOA to produce 2-aminophenol (2AP), while the FDB2 locus facilitates modification of 2AP by addition of a malonyl group to form HPMA. (B) 2-Oxindole, a γ-lactam compound structurally similar to BOA.
