Table 2.
Clinical complications associated with mean tacrolimus trough concentration n (%)
| Complications post-LT | Low-cTAC group (n = 356) | High-cTAC group (n = 172) | P value |
| Overweight/obesity (BMI ≥ 25) | 76 (21.3) | 52 (30.2) | 0.026 |
| Hypertension | 48 (13.5) | 19 (11.0) | 0.431 |
| Dyslipidaemia | 98 (27.5) | 77 (44.8) | < 0.001 |
| Cardio-cerebral events | 12 (3.4) | 6 (3.5) | 0.944 |
| CKD | 52 (14.6) | 39 (22.7) | 0.021 |
| AR | 34 (9.6) | 24 (14.0) | 0.129 |
| CR | 10 (2.8) | 10 (5.8) | 0.090 |
| Infection | 88 (24.7) | 57 (33.1) | 0.042 |
| New-onset malignance | 8 (2.2) | 1 (0.6) | 0.304 |
cTAC: Tacrolimus trough concentration; BMI: Body mass index; LT: Liver transplantation; CKD: Chronic kidney disease; AR: Acute rejection; CR: Chronic rejection.