Table 1.
Group-wise bivariate correlation between expression of genes.
| Gene 1 | Gene 2 | Region | Group | rs | p | |
|---|---|---|---|---|---|---|
| HPA axis - HPA axis | Crhr1 | Nr3c1 | Hypothalamus | MS360 Es | 0.878 | 3.57E-07 |
| Crhr1 | Nr3c1 | Hypothalamus | MS360 Ws | 0.903 | 3.44E-04 | |
| Crhr1 | Oxt | Hypothalamus | MS15 Ws | 0.903 | 3.44E-04 | |
| Crhr1 | Oxt | Hypothalamus | MS360 Ws | 0.964 | 7.32E-06 | |
| Oxt | Avp | Hypothalamus | MS360 Es | 0.753 | 2.01E-04 | |
| HPA axis - DNA methylation | Crhr1 | Dnmt1 | Hypothalamus | MS15 Ws | 0.952 | 2.28E-05 |
| Crhr1 | Dnmt1 | Hypothalamus | MS360 Es | 0.798 | 2.44E-05 | |
| Crhr1 | Dnmt1 | Hypothalamus | MS360 Ws | 0.952 | 2.28E-05 | |
| Nr3c1 | Dnmt1 | Hypothalamus | AFR Es | 0.927 | 1.12E-04 | |
| Nr3c1 | Dnmt1 | Hypothalamus | MS15 Ws | 0.952 | 2.28E-05 | |
| Nr3c1 | Dnmt1 | Hypothalamus | MS360 Es | 0.949 | 1.88E-10 | |
| Nr3c1 | Dnmt1 | Hypothalamus | MS360 Ws | 0.964 | 7.32E-06 | |
| Crhr1 | Mecp2 | Hypothalamus | AFR Es | 0.927 | 3.97E-05 | |
| Crhr1 | Mecp2 | Hypothalamus | MS360 Ws | 0.939 | 5.48E-05 | |
| Oxt | Mecp2 | Hypothalamus | MS360 Ws | 0.939 | 5.48E-05 | |
| Nr3c1 | Mecp2 | Pituitary | MS360 Es | 0.805 | 1.90E-05 | |
AFR, animal facility reared; E, ethanol drinking; g, group housed; MS, maternal separation (15 or 360 min); rs, spearman’s correlation coefficient; s, single housed; W, water drinking.