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. 2016 Jan 25;11(1):e0147752. doi: 10.1371/journal.pone.0147752

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© 2016 Kossatz et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 2 — (A) Examples of clonogenic growth of FaDu and Cal27 cells without (0 Gy) and after 10 Gy irradiation. (B) Clonogenic survival curve of FaDu and Cal27 cells after 0, 2, 4, 6, 8 and 10 Gy irradiation. Means ± SEM of three independent experiments with three parallels each. The asterisk indicates a p-value < 0.05 between FaDu and Cal27 cells using Student’s t-test. (C) Nuclear PARPi-FL uptake without and after 10 Gy irradiation, as observed microscopically in FaDu cells and (D) Cal27 cells. Nuclear localization was confirmed by Hoechst DNA stain. Representative images from n = 3 experiments.