Table I.

Quantitative analysis of the immunohistochemical results.

Dependent variables	Mean difference from negative control ± standard error	P-value	95% confidence interval
Area
CIN I	−42.69±12.96	0.01a	(−77.92 to −7.46)
CIN II	−60.80±13.61	<0.001a	(−97.80 to −23.80)
CIN III	−46.27±13.25	0.01a	(−82.30 to −10.24)
Density
CIN I	7.71±5.49	0.51	(−7.22 to 22.63)
CIN II	−5.77±5.77	0.75	(−21.45 to 9.91)
CIN III	−8.06±5.61	0.49	(−23.33 to 7.21)
Diameter
CIN I	−0.69±0.50	0.52	(−2.06 to 0.67)
CIN II	−1.40±0.53	0.06	(−2.83 to 0.04)
CIN III	0.39±0.51	0.87	(−1.01 to 1.78)
IOD
CIN I	−4,604.65±2,485.56	0.27	(−11,363.15 to −2,153.86)
CIN II	−8,311.75±2,610.36	0.02a	(−15,409.60 to −1,213.90)
CIN III	−8,637.23±2,541.78	0.01a	(−15,548.61 to −1,725.85)

^aP<0.05. CIN, cervical intraepithelial neoplasia; IOD, integral optical density.