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FLT3-ITD Consistently Deregulates the Same Genes in AML
(A–C) Average mRNA microarray values for FLT3-ITD target genes in 2 datasets obtained from 461 (Verhaak et al., 2009) or 200 (Cancer Genome Atlas Research Network, 2013) AML samples.
(A) Average profiles for 134 upregulated genes, with a subset of validated genes listed on the right.
(B) Average profiles for 77 downregulated genes.
(C) Profiles for individual upregulated genes.
