Figure 3.
Integrated regulatory network. (A) Integrated network of module 1 and miRNA regulatory network. (B) Integrated network of module 2 and miRNA regulatory network. (C) Integrated network of module 3 and miRNA regulatory network. Diamond-shaped nodes represent miRNA and circular nodes represent DEGs. Orange and blue nodes represent products of up- and downregulated DEGs, respectively. Grey nodes represent PTC-associated genes that were not DEGs. Nodes with a purple edge represent PTC-associated genes that were collected in the Malacard database; and nodes with a green edge represent PTC-associated genes thatwere not collected in the Malacard database. miRNA, microRNA; DEG, differentially-expressed gene; PTC, papillary thyroid carcinoma.