Effects of paeoniflorin (PF) on the expression levels of nuclear factor (NF)-κB, tumor necrosis factor (TNF)-α, interleukin (IL)-1β and IL-6 in hepatic tissues 6 h following hepatic ischemia/reperfusion injury. The expression levels of (A) NF-κB, (B) TNF-α, (C) IL-1β and (D) IL-6, were detected in various groups. Data are presented as the mean ± standard deviation (n=6). **P<0.01 vs. the sham group; ##P<0.01 vs. the vehicle group. Sham, sham-operated; Vehicle, vehicle-treated; 5 mg/kg, PF (5 mg/kg)-treated group, 10 mg/kg, PF (10 mg/kg)-treated group, and 20 mg/kg, PF (20 mg/kg)-treated group.