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. Author manuscript; available in PMC: 2016 Jan 26.
Published in final edited form as: Integr Biol (Camb). 2015 Dec 2;8(1):62–72. doi: 10.1039/c5ib00199d

Figure 3. Cell attachment through E-selectin/Fc is enhanced on stiff substrates.

Figure 3

THP-1 cells were perfused at 100 s−1 across gels coated with E-selectin/Fc at 20 molecules/μm2. A) The percentage of attached cells increased with increasing substrate stiffness (n = 5 experiments, mean ± s.e., t-test for 1 vs 24 kPa: p = 0.015). B) Attached cells remained for longer periods of time on stiffer gels (n = 5 experiments, mean ± s.e., t-test for 1 vs 24 kPa: p = 0.11). C) Representative cell tracks plotted as distance traveled versus time.