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. Author manuscript; available in PMC: 2016 Jan 26.
Published in final edited form as: Integr Biol (Camb). 2015 Dec 2;8(1):62–72. doi: 10.1039/c5ib00199d

Figure 4. On a high density of E-selectin/Fc, cells roll slower on stiff gels.

Figure 4

THP-1 cells were perfused at 100 s−1 across gels coated with E-selectin/Fc at 152 molecules/μm2. A) The percentage of attached cells did not vary with substrate stiffness (n = 3 experiments, mean ± s.e., t-test for 1 vs 24 kPa: p = 0.44). B) The rolling speed of attached cells decreased with increasing substrate stiffness (n = 3 experiments, mean ± s.e., t-test for 1 vs 24 kPa: p = 0.078). C) Representative cell tracks plotted as distance traveled versus time.