Table 2.

Nucleophile scope with linchpin 15.^[a]

Entry	NuLi	Product	Yield
1	MeLi	24	78%
2		25	71%
3		26	53%
4		27	66%
5		28	74%
6		29	71%
7		(R)-30	59%
8		(R)-31	68%[b]
9		(R)-32	63%[b]
10		(R)-33	64%[b]

^[a]Reaction conditions: i) 15, THF, –78° C, then slow addition of NuLi; ii) BnBr, HMPA, THF, –78° C to –30° C; iii) sat. aq. NH₄Cl.

^[b]i) 15, THF,–78 ° C, then slow addition of NuLi; ii) BnBr, THF, then slow addition of HMPA/THF solution, –78° C to –30° C; iii) sat. aq. NH₄Cl.