Table II.
Clinical information of tumors with TERT mutations.
| Case | Age/sex | Location | Diagnosis | Mutation | Treatment | Prognosis |
|---|---|---|---|---|---|---|
| 96 | 47/F | R. lower leg | Myxoid liposarcoma with RC | C228T | CTx+WR+CTx | NED (58 mos) |
| 276 | 58/M | R. thigh | Malignant granular cell tumor | C228T | WR | NED (72 mos) |
| 278 | 60/M | R. thigh | Pleomorphic sarcoma | C228T | WR | Lung metastasis (46 mos) |
| Alive with NED (103 mos) | ||||||
| 280 | 56/M | R. thigh | Myxoid liposarcoma | C228T | WR+RTx | NED (61 mos) |
| 370 | 43/M | L. thigh | Myxoid liposarcoma with RC | C228T | WR+CTx | NED (43 mos) |
TERT, telomerase reverse transcriptase; F, female; M, male; R, right; L, left; RC, round cell; CTx, chemotherapy; WR, wide resection; RTx, radiation therapy NED; no evidence of disease.