Table 1.
No. of patients |
Expression of VEGF-C |
P value |
Expression of CCR7 |
P value | |||
Positive | Negative | Positive | Negative | ||||
Age | NS* | NS | |||||
<61 years | 46 | 21 | 25 | 23 | 23 | ||
≥61years | 72 | 41 | 31 | 40 | 32 | ||
Gender | NS | NS | |||||
Male | 71 | 38 | 33 | 39 | 32 | ||
Female | 47 | 24 | 23 | 24 | 23 | ||
Tumor size | NS | <0.01 | |||||
<5 cm | 53 | 23 | 30 | 21 | 32 | ||
≥5 cm | 65 | 39 | 26 | 42 | 23 | ||
Tumor location | NS | NS | |||||
Lower third (L) | 81 | 40 | 41 | 44 | 37 | ||
Middle third (M) | 21 | 12 | 9 | 11 | 10 | ||
Upper third (U) | 16 | 10 | 6 | 8 | 8 | ||
Lauren classification | NS | NS | |||||
Intestinal | 53 | 24 | 29 | 25 | 28 | ||
Diffuse | 53 | 30 | 23 | 32 | 21 | ||
Mixed | 12 | 8 | 4 | 6 | 6 | ||
Depth of invasion | NS | <0.001 | |||||
T1/2 | 24 | 9 | 15 | 5 | 19 | ||
T3/4 | 94 | 53 | 41 | 58 | 36 | ||
Lymph node metastasis | <0.001 | <0.001 | |||||
Positive | 61 | 45 | 16 | 50 | 11 | ||
Negative | 57 | 17 | 40 | 13 | 44 | ||
Lymphatic invasion | <0.001 | <0.001 | |||||
Positive | 68 | 48 | 20 | 51 | 17 | ||
Negative | 50 | 14 | 36 | 12 | 38 | ||
Vascular invasion | <0.01 | NS | |||||
Positive | 35 | 25 | 10 | 20 | 15 | ||
Negative | 83 | 37 | 46 | 43 | 40 | ||
Stage | <0.001 | <0.001 | |||||
I, II | 55 | 19 | 36 | 13 | 42 | ||
III, IV | 63 | 43 | 20 | 50 | 13 |
*NS, not significant.