Table 1.
Change in concentrations of laboratory data (mean ± SD)
| Laboratory Variable | Before therapy | 4 wk | 8 wk | 12 wk |
| AST (IU/L) | 29.9 ± 8.1 | 50.0 ± 36.3 | 46.6 ± 24.9 | 46.9 ± 28.3 |
| ALT(IU/L) | 31.1 ± 13.2 | 48.6 ± 35.2 | 57.0 ± 38.9 | 48.4 ± 42.5 |
| ALP (IU/L) | 285.0 ± 114.8 | 238.5 ± 88.4 | 200.6 ± 76.7a | 186.9 ± 76.2a |
| γ-GTP(IU/L) | 149.6 ± 143.0 | 147.0 ± 178.6 | 128.8 ± 128.1 | 125.2 ± 110.3 |
| LDH (IU/l) | 311.2 ± 46.7 | 318.4 ± 44.8 | 320.1 ± 59.9 | 324.6 ± 59.2 |
| TB (mg/dl) | 0.7 ± 0.7 | 0.4 ± 0.2 | 0.6 ± 0.4 | 0.6 ± 0.5 |
| IgG (mg/dl) | 1 431.4 ± 285.3 | - | - | 1 415.0 ± 316.1 |
| IgM (mg/dl) | 255.8 ± 85.9 | - | - | 192.9 ± 67.5a |
a
P < 0.05 (baseline-matched t-test) vs the serum concentrations prior to the treatment.