Table I.
Cathepsin D | Cathepsin G | Cathepsin K | Cathepsin L | Cathepsin V | VEGF | RECK | |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Variable | L | H | P | L | H | P | L | H | P | L | H | P | L | H | P | L | H | P | L | H | P |
Cathepsin B | |||||||||||||||||||||
− | 55 | 8 | 0.036 | 49 | 17 | 0.105 | 36 | 16 | 0.830 | 52 | 14 | 0.002 | 42 | 18 | 0.439 | 30 | 38 | 0.100 | 43 | 29 | 0.625 |
+ | 41 | 16 | 39 | 25 | 37 | 15 | 33 | 29 | 48 | 15 | 17 | 40 | 35 | 28 | |||||||
Cathepsin D | |||||||||||||||||||||
− | – | – | – | 89 | 28 | 0.016 | 67 | 26 | 0.969 | 82 | 30 | 0.003 | 85 | 24 | 0.006 | 45 | 68 | 0.152 | 80 | 37 | 0.248 |
+ | – | – | – | 18 | 15 | 21 | 8 | 15 | 18 | 17 | 15 | 8 | 23 | 18 | 14 | ||||||
Cathepsin G | |||||||||||||||||||||
− | – | – | – | – | – | – | 75 | 21 | 0.023 | 81 | 30 | 0.035 | 84 | 25 | 0.025 | 41 | 69 | 0.925 | 78 | 31 | 0.073 |
+ | – | – | – | – | – | – | 21 | 15 | 25 | 20 | 26 | 18 | 16 | 26 | 22 | 21 | |||||
Cathepsin K | |||||||||||||||||||||
− | – | – | – | – | – | – | – | – | – | 68 | 26 | 0.124 | 69 | 23 | 0.747 | 36 | 55 | 0.180 | 66 | 33 | 0.259 |
+ | – | – | – | – | – | – | – | – | – | 21 | 15 | 26 | 10 | 10 | 27 | 22 | 17 | ||||
Cathepsin L | |||||||||||||||||||||
− | – | – | – | – | – | – | – | – | – | – | – | – | 78 | 27 | 0.292 | 44 | 58 | 0.032 | 72 | 37 | 0.111 |
+ | – | – | – | – | – | – | – | – | – | – | – | – | 31 | 16 | 12 | 36 | 27 | 24 | |||
Cathepsin V | |||||||||||||||||||||
− | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | 45 | 62 | 0.059 | 70 | 45 | 0.673 |
+ | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | 11 | 32 | 24 | 18 | ||
VEGF | |||||||||||||||||||||
− | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | 47 | 12 | 0.001 |
+ | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | 54 | 46 |
L, low expression; H, high expression; VEGF, vascular endothelial growth factor; RECK, reversion-inducing cysteine-rich protein with Kazal motifs.