Figure 1.
ZEB1 expression in ovarian carcinoma. (A) Poorly differentiated ovarian carcinoma exhibiting negative immunostaining for ZEB1, while most of the stromal cells surrounding the tumor cells exhibit strongly positive nuclear staining (magnification, ×200). (B) Another poorly differentiated ovarian carcinoma exhibiting positive nuclear immunostaining of both tumor and stromal cells (magnification, ×200). (C) The stromal cells in a well-differentiated ovarian carcinoma were all strongly positive, while the tumor cells were negative for ZEB1 (magnification, ×200). (D) Both the tumor and stromal cells in a well-differentiated ovarian carcinoma exhibited positive nuclear staining (magnification, ×200). ZEB1, zinc finger E-box-binding homeobox factor 1.