Table III.

Association between the expression levels of miR-10a, miR-342-3p and TIAM1 protein in tissues of patients with ENKTCL and the demographic and clinical features of the patients.

		miR-10a		miR-342-3p		TIAM1
Clinical feature	Cases (no.)	Expression (×10−3)a	P-valueb	Expression (×10−3)a	P-valueb	Cases (no.)	TIAM1+ cases (no.)	P-valuec
Age (years)			0.02		0.97			0.34
﹤60	13	4.97±1.13		2.08±0.27		17	10
≥60	2	1.46±0.64		2.05±0.73		4	1
Gender			0.58		0.70			0.92
Male	12	4.03±1.02		2.02±0.28		17	9
Female	3	6.41±3.43		2.29±0.56		4	2
Ann Arbor stage			0.98		0.22			0.02
I–II	6	4.46±1.98		1.68±0.41		9	2
III–IV	9	4.54±1.20		2.34±0.28		12	9
LDH levels			0.93		0.90			0.51
High	6	4.39±1.72		2.12±0.44		10	6
Normal	9	4.59±1.36		2.05±0.3		11	5
B symptoms			0.06		0.88			0.53
Positive	8	6.28±1.53		2.11±0.32		12	7
Negative	7	2.48±0.93		2.04±0.39		9	4
IPI (score)			0.61		0.21			0.02
0–2	7	3.90±1.77		1.74±0.35		9	2
3–5	8	5.04±1.24		2.37±0.32		12	9

^aExpression measured relative to U6;

^bStudents t-test;

^cχ² test. miR, microRNA; TIAM1, T-lymphoma invasion and metastasis inducing factor 1; ENKTCL, extranodal natural killer/T-cell lymphoma, nasal type; LDH, lactate dehydrogenase; IPI, international prognostic index.