Table I.
Characteristics | Non-ASCT (n=72) | ASCT (n=42) |
---|---|---|
Age, years | ||
Median (range) | 57 (29–65) | 53 (41–65) |
Gender, male/female | 43/29 | 30/12 |
M component, n (%) | ||
IgG | 41 (57.0) | 25 (59.5) |
IgA | 19 (26.4) | 6 (14.3) |
IgD | 2 (2.7) | 5 (11.9) |
Light chain | 10 (13.9) | 6 (14.3) |
DS stage, n (%) | ||
I | 0 | 0 |
II | 15 (20.8) | 14 (33.3) |
III | 57 (79.2) | 28 (66.7) |
ISS stage, n (%) | ||
I | 1 (1.4) | 1 (2.4) |
II | 61 (84.7) | 32 (76.2) |
III | 10 (13.9) | 9 (21.4) |
Number of induction cycles, median (range) | 5 (2–10) | 4 (3–8) |
Best response after induction therapy, n (%) | ||
CR | 19 (26.4) | 13 (31.0) |
VGPR | 22 (30.6) | 14 (33.3) |
PR | 31 (43.0) | 15 (35.7) |
Induction regimen, n (%) | ||
Bortezomib | 55 (76.4) | 25 (59.5) |
Thalidomide | 17 (23.6) | 17 (40.5) |
Maintenance therapy, n (%) | ||
Yes | 40 (55.6) | 25 (59.5) |
No | 32 (44.4) | 17 (40.5) |
ASCT, autologous hematopoietic stem cell transplantation; DS, Durie-Salmon staging system; ISS, International Staging System; CR, complete response; PR, partial response; VGPR, very good PR.