Table III.

Changes in body weight and mortality rate of nude mice with SW1116 xenografts (n=8 per group).

	Change in body weight
Treatment	Day 0	Day 6	Day 12	Day 18	Day 24	Day 30	Mortality
Control	18.6±0.8	19.0±0.7	20.3±1.0	20.9±1.5	21.5±1.4	21.9±1.4	1
SIN (25 mg/kg)	19.2±0.8	19.1±1.1	19.9±0.9	20.3±1.0	21.5±1.2	22.1±1.3	0
SIN (50 mg/kg)	19.6±1.0	19.8±1.2	19.4±2.9	21.5±1.3	21.8±1.4	20.9±2.6	1
SIN (100 mg/kg)	17.9±1.1	18.0±1.2	18.7±1.2	18.8±1.7	19.5±2.2a	18.2±4.0b	2
5-fluorouracil	17.7±1.0	18.1±1.1	18.4±1.7a	19.1±3.0	21.4±1.5	22.2±1.3	0

SIN, sinomenine.

^aP<0.05,

^bP<0.01.