Table III.

Multivariate analysis, including immunostaining for GADD45A.

Parameter	Risk ratio	95% CI	P-value
Primary tumor			0.019
T1	1.000
T2–4	15.384	1.552–142.857
Lymph node metastasis			0.004
N0-2	1.000
N3–4	3.333	1.472–7.518
Lymphatic invasion			0.305
Negative	1.000
Positive	0.391	0.065–2.341
Vein invasion			0.302
Negative	1.000
Positive	1.524	0.684–3.401
Immunostaining for GADD45A			0.018
Positive	1.000
Negative	2.486	1.168–5.290

CI, confidence interval; GADD45A, growth arrest and DNA damage-inducible 45α; T, tumor; N, node.