Table 1. - Percentage of leprosy cases detected during follow-up in different longitudinal studies with contacts of leprosy cases.
Study: Author, year of first publication, references | Study 1 | Total duration of follow-up | Percentage of cases per follow-up period in the control group |
---|---|---|---|
Moet, 2008 14 , 24 | RCT for chemoprophylaxis | 5-6 years | Total: 108 1-2 years: 67 (62.0%) 3-4 years: 24 (22.2%) 5-6 years: 17 (15.7%) |
Neelan, 1983 25 | RCT for chemoprophylaxis | Up to 180 weeks (~3.4 years) | Total: 42 Up to 90 weeks: 37 (88%) |
Noordeen, 1976 29 , 31 | RCT for chemoprophylaxis | Contacts of "non-lepromatous cases" = 3.5 years (185 weeks) | Total: 109 Up to 119 weeks (~ 2.2 years): 84 (77%) |
Contacts of lepromatous cases = 6 years (318 weeks) | Total: 38 Up to 150 weeks (~ 2.8 years): 34 (89%) | ||
Dharmendra, 1965 9 , 10 , 28 , 30 | RCT for chemoprophylaxis | 3rd report up to 299 weeks (~ 5.6 years) (Last report up to 8 1/2 years but with small cases of follow-up) | Total with 299 weeks: 48 Up to 149 weeks (~2.8 years): 39 (81%) |
Stanley, 1981 45 | RCT for BCG in contacts | 8 years | Total: 192 cases 2 Separately for survey and mean years for entry: 1st (mean 1.9 years): 103 (54%) 2nd (mean 3.3 years): 51 (27%) 3rd (mean 5.7 years): 27 (14%) 4th (mean 8.0 years): 11 (6%) |
Notes: 1RCT randomised control trial; 2as in table 6 of the reference.