Fig. 7.

Effects of i.v. injection of C-II-a into Apoc2 mutant mice. (A) Analysis of plasma lipids. 200 microliters of C-II-a peptide (0.2, 1.0, and 5.0 μmol/kg of body weight) was injected into the retro-orbital sinus of Apoc2 mutant mice (n = 3 per groups). Lipid levels were measured in the plasma at 0, 0.5, 1, 2, 4, 7, 24, and 48 hours after C-II-a injection. Data are the mean ± S.E.M. (B) Distribution of lipids in plasma analyzed by FPLC. 50 microliters of plasma pooled from three mice was separated by FPLC. The level of TC and TG in the fractions was measured at 0, 2, 24, and 48 hours after C-II-a injection (5.0 μmol/kg of body weight).