TABLE 2.
aGeometric Mean (Geometric %COV) |
|||||
---|---|---|---|---|---|
0.5 mg (n = 2) | 2 mg (n = 4) | 4 mg (n = 2) | 10 mg (n = 4) | 25 mg (n = 1) | |
Cmax (ng/ml) | 0.53–0.90 | 4.20 (71%) | 4.21–5.63 | 12.6 (61%) | 15.2 |
btmax (h) | 1.00–2.55 | 2.50 (1.00–4.00) | 1.00–4.00 | 2.50 (2.50–4.00) | 4.07 |
AUC (0–tlast) (ng ∣ h / ml) | 2.42–3.66 | 28.4 (45%) | 39.5–62.1 | 112 (45%) | 154 |
The range for all parameters is reported where n = 2. Individual parameter is reported where n = 1.
Median (range).