TABLE 4.

Receptor occupancy and nondisplaceable distribution volume (V_ND) estimates

LY2456302 Dose	2.5 h Postdose		24 h Postdose
	Occupancy	VND	Occupancy	VND
	%	ml/cm3	%	ml/cm3
0.5 mg (n = 2)	35 ± 4	1.23 ± 0.06	19 ± 3	1.92 ± 0.21
2 mg (n = 4)	71 ± 10	1.32 ± 0.19	43 ± 14	1.41 ± 0.25
4 mg (n = 2)	79 ± 6	1.43 ± 0.10	48 ± 1	1.37 ± 0.03
10 mg (n = 3)	94 ± 0.5	1.43 ± 0.10	72 ± 4	1.51 ± 0.10
25 mg (n = 1)	93	1.50	82	1.40

Data are mean ± S.D. Individual parameters are reported where n = 1.