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. 2015 Nov 13;11(1):723–730. doi: 10.3892/ol.2015.3913

Table I.

Association between LRP or survivin expression and clinical characteristics in non-small cell lung cancer.

Survivin expression, n (%) LRP expression, n (%)


+ P-value + P-value
Age, years 55.9±12.3 53.9±10.9 0.557 57.8±11.5 53.4±11.1 0.207
Gender
  Male 13 (81.25) 33 (73.30) 0.528 13 (92.86) 33 (70.21)
  Female   3 (18.75) 12 (26.67) 1 (7.14) 14 (29.79)
Smoking status
  Current or former smokers   7 (43.75) 27 (60.00) 0.261   6 (42.86) 28 (59.57) 0.269
  Non-smokers   9 (56.25) 18 (40.00)   8 (57.14) 19 (40.43)
Histology
  Squamous cell carcinoma   8 (50.00) 25 (55.56) 0.896 10 (71.43) 23 (48.94) 0.330
  Adenocarcinoma   6 (37.50) 14 (31.11) 3 (7.14) 17 (36.17)
  Adenosquamous carcinoma   2 (12.50)   6 (13.33)     1 (100.00)   7 (14.89)
Differentiation
  Low level   16 (100.00) 37 (82.22) 0.195   14 (100.00) 39 (82.98) 0.254
  Medium level 0 (0.00)   7 (15.56) 0 (0.00)   7 (14.89)
  High level 0 (0.00) 1 (2.22) 0 (0.00) 1 (2.13)
TNM stage
  IIIB   7 (43.75) 14 (31.11) 0.361   8 (57.14) 13 (27.66) 0.042
  IV   9 (56.25) 31 (68.89)   6 (42.86) 34 (72.34)
T stage
  T1   2 (12.50) 1 (2.22) 0.001 1 (7.14) 2 (4.26) 0.149
  T2   3 (18.75) 20 (41.44)   2 (14.29) 21 (44.68)
  T3   2 (12.50) 18 (40.00)   5 (35.71) 15 (31.91)
  T4   9 (56.25)   6 (13.33)   6 (42.86)   9 (19.15)
N stage
  N0 0 (0.00) 3 (6.67) 0.638 1 (7.14) 2 (4.26) 0.952
  N1   3 (18.75)   5 (11.11) 2 (14.29)   6 (12.77)
  N2   6 (37.50) 19 (42.22) 5 (35.71) 20 (42.55)
  N3   7 (43.75) 18 (40.00) 6 (42.86) 19 (40.43)
M stage
  M0   7 (43.75) 14 (31.11) 0.361   8 (57.14) 13 (27.66) 0.042
  M1   9 (56.25) 31 (68.89)   6 (42.86) 34 (72.34)

TNM, tumor-node-metastasis; LRP, lung resistance protein.