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. 2015 Nov 10;11(1):125–133. doi: 10.3892/ol.2015.3904

Table I.

Top two enriched GO biological process term clusters with the highest enrichment score for the upregulated differentially-expressed genes.

Enrichment score Term Description Count P-value Genes
7.432 GO:0007049 Cell cycle 31   1.08×10−12 SPC25, CCNA2, CENPF, NUSAP1, CDC20, NDC80, CCNB1, PTTG1, CCNB2, BUB1B
GO:0022403 Cell cycle phase 23   1.10×10−12 NUSAP1, CENPF, NDC80, CDC20, CCNB1, PTTG1, SPC25, CDKN1A, PLK1, BUB1B
GO:0022402 Cell cycle process 27   3.26×10−12 PTTG1, SPC25, CDKN2C, CENPF, NUSAP1, CDC20, NDC80, CCNB1, CDKN1C, BUB1B
GO:0000279 M phase 19   3.09×10−11 NUSAP1, CENPF, NDC80, CDC20, PTTG1, CCNB1, SPC25, PLK1, BUB1B, SKA3
GO:0051301 Cell division 14 1.25×10−7 NUSAP1, CDC20, PTTG1, CCNB1, SPC25, CCNB2, PLK1, BUB1B, TOP2A, CCNA2
GO:0000087 M phase of mitotic cell cycle 12 2.16×10−7 CCNB1, SPC25, PLK1, NUF2, NUSAP1, BUB1B, SKA3, CENPF, CDC20, PTTG1
GO:0000278 Mitotic cell cycle 16 5.40×10−7 NUSAP1, CENPF, NDC80, CDC20, PTTG1, CCNB1, SPC25, CDKN1A, CDKN2C, BUB1B
GO:0000280 Nuclear division 10 1.09×10−5 CCNB1, SPC25, KIF11, PLK1, NUF2, NUSAP1, BUB1B, SKA3, CDC20, PTTG1
GO:0007067 Mitosis 10 1.09×10−5 CCNB1, SPC25, KIF11, PLK1, NUF2, NUSAP1, BUB1B, SKA3, CDC20, PTTG1
GO:0048285 Organelle fission 10 1.74×10−5 CCNB1, SPC25, KIF11, PLK1, NUF2, NUSAP1, BUB1B, SKA3, CDC20, PTTG1
GO:0051439 Regulation of ubiquitin-protein ligase activity during mitotic cell cycle   4 4.86×10−2 CCNB1, PLK1, BUB1B, CDC20
5.335 GO:0000279 M phase 19   3.09×10−11 NUSAP1, CENPF, NDC80, CDC20, PTTG1, CCNB1, SPC25, PLK1, BUB1B, SKA3
GO:0051327 M phase of meiotic cell cycle   7 2.32×10−4 ADCY3, KIF2C, MKI67, PLK1, SGOL2, PTTG1, RAD51
GO:0007126 Meiosis   7 2.32×10−4 ADCY3, KIF2C, MKI67, PLK1, SGOL2, PTTG1, RAD51
GO:0051321 Meiotic cell cycle   7 2.76×10−4 ADCY3, KIF2C, MKI67, PLK1, SGOL2, PTTG1, RAD51

GO, gene ontology.