Figure 2.
Splenocytes incubated with breast cancer cell-derived exosomes exhibit lower [3H] thymidine incorporation compared with controls. Additionally, splenocytes incubated with exosomes produced under hypoxic conditions exhibit significantly lower incorporation compared with those produced under normoxic conditions for the cancer cell lines, MDA-MB-231 and BT-474. Bars represent mean ± standard error of the mean numbers of thymidine incorporation (cpm) from three independent experiments. *P<0.05. TdR, radioactive thymidine.