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. 2015 Oct 27;11(1):385–392. doi: 10.3892/ol.2015.3830

Table I.

GO-BP terms and KEGG pathways enriched by upregulated genes.

A, GO-BP terms

Term Description Count P-value
GO:0015837 Amine transport 5 5.95×10−3
GO:0006865 Amino acid transport 4 1.78×10−2
GO:0007167 Enzyme-linked receptor protein signaling pathway 7 1.85×10−2
GO:0051674 Localization of cell 6 4.03×10−2
GO:0048870 Cell motility 6 4.03×10−2
GO:0035239 Tube morphogenesis 4 4.32×10−2
GO:0001501 Skeletal system development 6 4.62×10−2
GO:0035295 Tube development 5 4.63×10−2

B, Enriched KEGG pathways

Term Description Count P-value

hsa04012 ErbB signaling pathway 3 8.21×10−2
hsa05216 Thyroid cancer 2 1.48×10−1
hsa00512 O-glycan biosynthesis 2 1.53×10−1
hsa04514 CAMs 3 1.64×10−1
hsa00071 Fatty acid metabolism 2 1.99×10−1
hsa05219 Bladder cancer 2 2.08×10−1
hsa05213 Endometrial cancer 2 2.51×10−1
hsa05221 Acute myeloid leukemia 2 2.75×10−1
hsa03320 PPAR signaling pathway 2 3.19×10−1
hsa04810 Regulation of actin cytoskeleton 3 3.33×10−1
hsa04350 TGF-β signaling pathway 2 3.84×10−1
hsa04060 Cytokine-cytokine receptor interaction 3 4.27×10−1
hsa05200 Pathways in cancer 3 5.48×10−1
hsa04310 Wnt signaling pathway 2 5.71×10−1
hsa04144 Endocytosis 2 6.45×10−1
hsa04510 Focal adhesion 2 6.78×10−1
hsa04080 Neuroactive ligand-receptor interaction 2 7.66×10−1
hsa04010 MAPK signaling pathway 2 7.80×10−1
hsa04740 Olfactory transduction 2 8.86×10−1

Term, identification number of GO term or KEGG pathway; Description, name of GO term or KEGG pathway; Count, number of genes enriched in GO term or KEGG pathway; GO, Gene Oncology; KEGG, Kyoto Encyclopedia of Genes and Genomes; BP, biological process; CAMs, cell adhesion molecules; MAPK, mitogen-activated protein kinase; TGF-β, transforming growth factor-β; PPAR, peroxisome proliferator-activated receptor.