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. Author manuscript; available in PMC: 2016 Jan 26.
Published in final edited form as: J Pathol. 2011 Oct 18;226(1):40–49. doi: 10.1002/path.2996

Figure 1.

Figure 1

Increased embryonal rhabdomyosarcoma (eRMS) incidence and decreased age of onset in p53-deficient mdx mice. Mice defective in expression of p53 (Trp53), mice defective in the expression of dystrophin (mdx), and mice partially or completely deficient in p53 and dystrophin (Trp53+/− mdx or Trp53−/− mdx) were assessed for development of rhabdomyosarcoma at different ages. All muscle-derived RMS identified were embryonal RMS (eRMS). Data are reported as a percentage of the total animals for each individual genotype. n = 450 Trp53+/+ (wild-type), 26 Trp53+/−, 22 Trp53−/−, 360 Trp53+/+ mdx, 56 Trp53+/− mdx and 22 Trp53−/− mdx animals.