Fig. 5.
C16:0 ceramide and S1P in murine NASH. A: Circulating EVs were measured in 100 μl of plasma from mice fed either chow (n = 9) or the FFC NASH-inducing diet (n = 10) for 24 weeks. C16:0 ceramide (B) and S1P (C) were measured in EVs isolated from 100 μl of plasma from the mice described in (A). C16:0 ceramide (D) and S1P (E) were measured in liver samples from the mice described in (A). *P < 0.05 for the comparisons shown.