Corneal backscatter as a function of severity of Fuchs' dystrophy. Backscatter (in SU) in the anterior cornea measured by both instruments increased with severity of the disease. In the midcornea, the relationship with disease severity was slightly weaker than in the anterior cornea by Scheimpflug photography and not significant by confocal microscopy. In the posterior cornea, when measured by Scheimpflug photography, backscatter increased with disease severity, but when measured by confocal microscopy backscatter trended weakly downward. In regression equations, S = backscatter from Scheimpflug camera, C = backscatter from confocal microscope, Gr = grade of severity of Fuchs' endothelial dystrophy (grades 1–6) and normal (grade 0).